Syn-ake – Line smoothing peptide


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SYN-AKE ® is a synthetic peptide that provides a safe and effective alternative to “Botox” in the treatment of facial expression lines.
The inspiration for SYN®-AKE came from an active component in the venom of the temple viper, in its ability to inhibit muscle contractions. DSM created a synthetic peptide that mimics this property of the venom, and which is able to quickly and safely reduce the facial muscle contraction in a completely reversible manner, without the need for costly injections or clinical procedures.

In-vivo studies on crow’s feet lines and forehead wrinkles demonstrate excellent skin smoothing and anti-wrinkle effects when compared to placebo and competitor peptides. The effect is temporary and the line relaxing properties will wear off after 12 hours – a kind of Cinderella effect.

INCI – Glycerin (and) Aqua (and) Dipeptide Diaminobutyroyl Benzylamide Diacetate

Usage Rate: Up to 5%

Can be added to creams, lotions, and serums. Add at temperatures below 40C.

Warning – Do not apply the solution neat to the skin. It must be incorporated into a suitable cream or serum at the recommended usage rate,

Additional information


20g, 50g, 100g

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MSDS Syn-ake


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